A rapid test for the qualitative detection of IgG and IgM antibodies to Salmonella typhi (S. typhi) in human serum or plasma For professional in vitro diagnostic use only.
Typhoid fever is caused by S. typhi, a Gram-negative bacterium. World-wide an estimated 17 million cases and 600,000 associated deaths occur annually1 . Patients who are infected with HIV are at significantly increased risk of clinical infection with S. typhi2 . Evidence of h. pylori infection also presents an increased risk of acquiring typhoid fever. 1-5% of patients become chronic carrier harboring S. typhi in the gallbladder. The clinical diagnosis of typhoid fever depends on the isolation of S. typhi from blood, bone marrow or a specific anatomic lesion in the facilities that cannot afford to perform this complicated and time consuming procedure, WidalTest (also referred as WeilFelix Test) is used to facilitate the diagnosis. However, many limitations lead to difficulties in the interpretation of the Widal test 3, 4 . In contrast, the Typhoid Rapid Test Cassette is a simple and rapid laboratory test. The test simultaneously detects and differentiates the IgG and the IgM antibodies to S. typhi specific antigen5 in serum or plasma thus aid in the determination of current or previous exposure the S. typhi.
Materials Provided
