Cotinine (Nicotine) - Lab Solutions: Rapid test, antigen test, rapid pcr test, elisa testing Lab Solutions: Rapid test, antigen test, rapid pcr test, elisa testing
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Cotinine (Nicotine)

 COT Rapid Test Cassette (Urine)

A rapid test for the qualitative detection of Cotinine (nicotine metabolite) in human urine. For determination of smoking status only. Not intended for medical diagnostic use

SUMMARY of COT Rapid Test Cassette (Urine)

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays. In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.1 While cotinine is thought to be an inactive metabolite, it’s elimination profile is more stable than that of nicotine which is largely urine pH dependent. As a result, cotinine is considered a good biological marker for determining nicotine use. The plasma half-life of nicotine is approximately 60 minutes following inhalation or parenteral administration.2 Nicotine and cotinine are rapidly eliminated by the kidney; the window of detection for cotinine in urine at a cutoff level of 200 ng/mL is expected to be up to 2-3 days after nicotine use. The COT Rapid Test Cassette (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Cotinine in urine. The COT Rapid Test Cassette (Urine) yields a positive result when the Cotinine in urine exceeds 200 ng/mL

Materials Provided

  1. 25Test cassettes
  2. Droppers 
  3. Package insert

  • Name: Cotinine (Nicotine)
  • Brand: Right Sign
  • Speciman: urine
  • Pack: 25 cassette\ test

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